Summary
Monofluoracetic acid and trifluoracetic acid exsert a marked influence on growth and
metabolism of Aspergillus niger.
Monofluoracetic acid inhibits strongly the accumulation of citric acid and of total
acids. Oxalic acid and gluconic acid are accumulated predominantly if the mould is
grown in the presence of monofluoracetic acid. The possible mechanisms of these metabolic
shifts caused by monofluoracetic acid are discussed.
Trifluoracetic acid is much less toxic to Aspergillus niger and the metabolic disorders are different from those caused by monofluoracetic acid.